International Standard
ISO 23921:2020
Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke with an intense smoking regime — Method using LC-MS/MS
Reference number
ISO 23921:2020
Edition 1
2020-09
International Standard
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ISO 23921:2020
77347
Published (Edition 1, 2020)

ISO 23921:2020

ISO 23921:2020
77347
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CHF 96
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Abstract

This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of cigarette mainstream smoke with the intense smoking regime specified in ISO 20778 by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

General information

  •  : Published
     : 2020-09
    : International Standard published [60.60]
  •  : 1
     : 14
  • ISO/TC 126
    65.160 
  • RSS updates

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